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Antimetastatic effects of synthetic polypeptides containing repeated structures of the cell adhesive Arg-Gly-Asp (RGD) and Tyr-Ile-Gly-Ser-Arg (YIGSR) sequences.

We have investigated the inhibitory effect on experimental or spontaneous lung metastases of polypeptides which contain repetitive structures of the Arg-Gly-Asp (RGD) or Tyr-Ile-Gly-Ser-Arg (YIGSR) sequence derived from adhesion molecules, and studied their biological characterisation after administ...

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Bibliografske podrobnosti
Main Authors: Saiki, I., Murata, J., Iida, J., Sakurai, T., Nishi, N., Matsuno, K., Azuma, I.
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 1989
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2247318/
https://ncbi.nlm.nih.gov/pubmed/2803948
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