P-glycoprotein gene amplification and expression in multidrug-resistant murine P388 and B16 cell lines.

P-glycoprotein gene (mdrl) amplification and expression were examined in murine leukaemia P388/DX and melanoma B16VDXR cell lines, which exhibit a high level of resistance to a selecting agent, doxorubicin, and express a multidrug-resistant phenotype because they are cross-resistant to multiple cyto...

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Hauptverfasser: Capranico, G., De Isabella, P., Castelli, C., Supino, R., Parmiani, G., Zunino, F.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 1989
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2247236/
https://ncbi.nlm.nih.gov/pubmed/2567607
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