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Immunosuppression by immunoglobulin deaggregation is not effective in reducing the anti-xenogeneic immunoglobulin response: experimental and clinical studies.

A major complication of in vivo monoclonal antibody therapy in patients with cancer is the host's immune response to the administered xenogeneic immunoglobulin. We have performed parallel clinical and experimental studies to investigate the possibility that deaggregation of the therapeutic mono...

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Detalhes bibliográficos
Main Authors: Sivolapenko, G. B., Kanariou, M., Edwards, R. J., Epenetos, A. A., Ritter, M. A.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 1989
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2247117/
https://ncbi.nlm.nih.gov/pubmed/2803922
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