Intracellular localisation of a subunit of human DNA polymerase alpha affecting primase activity recognised by monoclonal antibody (HDR-854-E4) and its application to distinction between proliferative and non-proliferative lesions.

We have successfully established one murine hybridoma that secretes a monoclonal antibody specific for the 77,000 subunit of human DNA polymerase alpha. The results of immunochemical studies, using HDR-854-E4 monoclonal antibody (MAb) and immunoperoxidase detection methods, demonstrate intranuclear...

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Detalhes bibliográficos
Main Authors: Sugawara, I., Uchino, K., Morishita, Y., Yagura, T., Okamoto, S., Mori, S.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 1989
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2247022/
https://ncbi.nlm.nih.gov/pubmed/2765363
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