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5-FU therapeutic monitoring with dose adjustment leads to an improved therapeutic index in head and neck cancer.

This 4 year study reports on a pharmacokinetic study for the widely used regimen of cis-platin plus continuous 5-day 5-FU as first-line chemotherapy of head and neck cancer, and the benefit of such data for real-time therapy management. Pharmacokinetic analysis of 177 cycles for 77 patients from a g...

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Main Authors: Santini, J., Milano, G., Thyss, A., Renee, N., Viens, P., Ayela, P., Schneider, M., Demard, F.
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 1989
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2247002/
https://ncbi.nlm.nih.gov/pubmed/2930694
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