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Brefeldin A-inhibited guanine nucleotide-exchange activity of Sec7 domain from yeast Sec7 with yeast and mammalian ADP ribosylation factors

The Saccharomyces cerevisiae Sec7 protein (ySec7p), which is an important component of the yeast secretory pathway, contains a sequence of ≈200 amino acids referred to as a Sec7 domain. Similar Sec7 domain sequences have been recognized in several guanine nucleotide-exchange proteins (GEPs) for ADP...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Sata, Makoto, Donaldson, Julie G., Moss, Joel, Vaughan, Martha
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1998
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC22466/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9539714/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.8.4204
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