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The pharmacokinetics of medroxyprogesterone acetate following two different loading dose schedules in advanced carcinoma of the breast.

A loading dose of MPA employing a regimen of 1,000 mg six hourly for 8 doses can achieve plateau levels above 100 ng ml-1 within the first 36 h of treatment, without any untoward toxicity. This raises the possibility of shortening the time to response for this agent. The additional factor of the tim...

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Hlavní autoři: Canney, P. A., Dowsett, M., Priestman, T. J.
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 1988
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2246490/
https://ncbi.nlm.nih.gov/pubmed/2971386
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