Pharmacokinetics and pharmacodynamics of locoregional 5 fluorouracil (5FU) in advanced colorectal liver metastases.

By measuring peripheral drug levels in plasma, the effect of combining albumin microspheres with angiotensin II on systemic exposure to 5FU when administered by bolus injection into the hepatic artery in patients with advanced colorectal liver metastases has been assessed. The results suggest that d...

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Autores principales: Goldberg, J. A., Kerr, D. J., Willmott, N., McKillop, J. H., McArdle, C. S.
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 1988
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2246442/
https://ncbi.nlm.nih.gov/pubmed/3358909
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