The Drosophila NURF remodelling and the ATAC histone acetylase complexes functionally interact and are required for global chromosome organization

Drosophila Gcn5 is the catalytic subunit of the SAGA and ATAC histone acetylase complexes. Here, we show that mutations in Gcn5 and the ATAC component Ada2a induce a decondensation of the male X chromosome, similar to that induced by mutations in the Iswi and Nurf301 subunits of the NURF nucleosome...

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Detalhes bibliográficos
Main Authors: Carré, Clément, Ciurciu, Anita, Komonyi, Orbán, Jacquier, Caroline, Fagegaltier, Delphine, Pidoux, Josette, Tricoire, Hervé, Tora, Laszlo, Boros, Imre M, Antoniewski, Christophe
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2008
Assuntos:
Scientific Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2246414/
https://ncbi.nlm.nih.gov/pubmed/18084186
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.embor.7401141
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