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Broad network-based predictability of Saccharomyces cerevisiae gene loss-of-function phenotypes

We demonstrate that loss-of-function yeast phenotypes are predictable by guilt-by-association in functional gene networks. Testing 1,102 loss-of-function phenotypes from genome-wide assays of yeast reveals predictability of diverse phenotypes, spanning cellular morphology, growth, metabolism, and qu...

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Bibliografische gegevens
Hoofdauteurs: McGary, Kriston L, Lee, Insuk, Marcotte, Edward M
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2007
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2246260/
https://ncbi.nlm.nih.gov/pubmed/18053250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gb-2007-8-12-r258
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