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Methionine aminopeptidase-2 blockade reduces chronic collagen-induced arthritis: potential role for angiogenesis inhibition

The enzyme methionine aminopeptidase-2 (MetAP-2) is thought to play an important function in human endothelial cell proliferation, and as such provides a valuable target in both inflammation and cancer. Rheumatoid arthritis (RA) is a chronic inflammatory disease associated with increased synovial va...

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Autors principals: Bainbridge, John, Madden, Leigh, Essex, David, Binks, Michael, Malhotra, Rajneesh, Paleolog, Ewa M
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2007
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2246249/
https://ncbi.nlm.nih.gov/pubmed/18072970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar2340
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