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The quest for the Holy Grail: a disease-modifying osteoarthritis drug

The unfortunate story of the matrix metalloproteinase inhibitor PG116800, which had no effect on the osteoarthritic process but had unexpected side effects, highlights the following. First, reality does not always match the theory. Second, cell biology data must be interpreted within the context of...

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Autore principale: Berenbaum, Francis
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2007
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2246245/
https://ncbi.nlm.nih.gov/pubmed/18096086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar2335
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