CD40 signaling predicts response to preoperative trastuzumab and concomitant paclitaxel followed by 5-fluorouracil, epirubicin, and cyclophosphamide in HER-2-overexpressing breast cancer

INTRODUCTION: We performed gene expression analysis to identify molecular predictors of resistance to preoperative concomitant trastuzumab and paclitaxel followed by 5-fluorouracil, epirubicin, and cyclophosphamide (T/FEC). METHODS: Pretreatment fine-needle aspiration specimens from 45 patients with...

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Detalhes bibliográficos
Main Authors: Esteva, Francisco J, Wang, Jing, Lin, Feng, Mejia, Jaime A, Yan, Kai, Altundag, Kadri, Valero, Vicente, Buzdar, Aman U, Hortobagyi, Gabriel N, Symmans, W Fraser, Pusztai, Lajos
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2007
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2246190/
https://ncbi.nlm.nih.gov/pubmed/18086299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr1836
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