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Identification of a novel truncating PALB2 mutation and analysis of its contribution to early-onset breast cancer in French-Canadian women

BACKGROUND: PALB2 has recently been identified as a breast cancer susceptibility gene. PALB2 mutations are rare causes of hereditary breast cancer but may be important in countries such as Finland where a founder mutation is present. We sought to estimate the contribution of PALB2 mutations to the b...

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Autors principals: Foulkes, William D, Ghadirian, Parviz, Akbari, Mohammed Reza, Hamel, Nancy, Giroux, Sylvie, Sabbaghian, Nelly, Darnel, Andrew, Royer, Robert, Poll, Aletta, Fafard, Eve, Robidoux, André, Martin, Ginette, Bismar, Tarek A, Tischkowitz, Marc, Rousseau, Francois, Narod, Steven A
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2007
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2246183/
https://ncbi.nlm.nih.gov/pubmed/18053174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr1828
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