Functional Analysis of Mosquito-Borne Flavivirus Conserved Sequence Elements within 3′ Untranslated Region of West Nile Virus by Use of a Reporting Replicon That Differentiates between Viral Translation and RNA Replication

We have developed a reporting replicon of West Nile virus (WNV) that could be used to quantitatively distinguish viral translation and RNA replication. A Renilla luciferase (Rluc) gene was fused in-frame with the open reading frame of a subgenomic replicon in the position where the viral structural...

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Detalhes bibliográficos
Main Authors: Lo, Michael K., Tilgner, Mark, Bernard, Kristen A., Shi, Pei-Yong
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
Assuntos:
Replication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC224605/
https://ncbi.nlm.nih.gov/pubmed/12941911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.18.10004-10014.2003
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