T Cells Cause Acute Immunopathology and Are Required for Long-Term Survival in Mouse Adenovirus Type 1-Induced Encephalomyelitis

Infection of adult C57BL/6 (B6) mice with mouse adenovirus type 1 (MAV-1) results in dose-dependent encephalomyelitis. Utilizing immunodeficient mice, we analyzed the roles of T cells, T-cell subsets, and T-cell-related functions in MAV-1-induced encephalomyelitis. T cells, major histocompatibility...

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Bibliographic Details
Main Authors: Moore, Martin L., Brown, Corrie C., Spindler, Katherine R.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2003
Subjects:
Pathogenesis and Immunity
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC224599/
https://ncbi.nlm.nih.gov/pubmed/12941916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.18.10060-10070.2003
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