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Adsorption and elution characteristics of nucleic acids on silica surfaces and their use in designing a miniaturized purification unit
We report nucleic acid (NA) adsorption isotherms and elution profiles for silica surfaces and use these to design a miniaturized NA purification unit based on solid-phase extraction with silica beads. The procedure is based on a pressure drop equation for flow through a packed bed and allows estimat...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2245989/ https://ncbi.nlm.nih.gov/pubmed/18022378 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ab.2007.10.026 |
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