Human T-Cell Leukemia Virus Type 1 Envelope Glycoprotein gp46 Interacts with Cell Surface Heparan Sulfate Proteoglycans

The major receptors required for attachment and entry of the human T-cell leukemia virus type 1 (HTLV-1) remain to be identified. Here we demonstrate that a functional, soluble form of the HTLV-1 surface envelope glycoprotein, gp46, fused to an immunoglobulin Fc region (gp46-Fc) binds to heparan sul...

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Detalhes bibliográficos
Main Authors: Piñon, Josefina D., Klasse, P. J., Jassal, Sushma R., Welson, Sandy, Weber, Jonathan, Brighty, David W., Sattentau, Quentin J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
Assuntos:
Replication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC224595/
https://ncbi.nlm.nih.gov/pubmed/12941902
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.18.9922-9930.2003
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