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Prevalence of Factor H–Binding Protein Variants and NadA among Meningococcal Group B Isolates from the United States: Implications for the Development of a Multicomponent Group B Vaccine

BACKGROUND: Two promising recombinant meningococcal protein vaccines are in development. One contains factor H–binding protein (fHBP) variants (v.) 1 and 2, whereas the other contains v.1 and 4 other antigens discovered by genome mining (5 component [5C]). Antibodies against fHBP are bactericidal ag...

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Bibliografiske detaljer
Main Authors: Beernink, Peter T., Welsch, Jo Anne, Harrison, Lee H., Leipus, Arunas, Kaplan, Sheldon L., Granoff, Dan M.
Format: Artigo
Sprog:Inglês
Udgivet: 2007
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2245893/
https://ncbi.nlm.nih.gov/pubmed/17436227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1086/514821
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