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Improving Drug Dosing in Hospitalized Patients: Automated Modeling of Pharmacokinetics for Individualization of Drug Dosage Regimens

Many clinically useful drugs have a narrow range of blood concentrations which are both safe and efficacious. Inter-individual and intra-individual variation in drug disposition are important factors causing blood concentrations of drug to fall outside of the therapeutic range. Modeling of the pharm...

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Main Authors: Lenert, Leslie, Sheiner, Lewis, Blaschke, Terrence
Format: Artigo
Jezik:Inglês
Izdano: 1988
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2245287/
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