The Gammaherpesvirus m2 Protein Manipulates the Fyn/Vav Pathway through a Multidocking Mechanism of Assembly

To establish latent infections in B-cells, gammaherpesviruses express proteins in the infected B-cells of the host that spuriously activate signalling pathways located downstream of the B-cell receptor. One such protein is M2, a murine gammaherpesvirus 68-encoded molecule that activates the Vav1/Rac...

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Hauptverfasser: Pires de Miranda, Marta, Alenquer, Marta, Marques, Sofia, Rodrigues, Lénia, Lopes, Filipa, Bustelo, Xosé R., Simas, J. Pedro
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2008
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2244710/
https://ncbi.nlm.nih.gov/pubmed/18301737
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0001654
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