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Peptide ligand screening of α-synuclein aggregation modulators by in silico panning
BACKGROUND: α-Synuclein is a Parkinson's-disease-related protein. It forms aggregates in vivo, and these aggregates cause cell cytotoxicity. Aggregation inhibitors are expected to reduce α-synuclein cytotoxicity, and an aggregation accelerator has recently been reported to reduce α-synuclein cy...
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| Главные авторы: | , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
BioMed Central
2007
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2244645/ https://ncbi.nlm.nih.gov/pubmed/18005454 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-8-451 |
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