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Increased Toll-Like Receptor (TLR) 2 and TLR4 Expression in Monocytes from Patients with Type 1 Diabetes: Further Evidence of a Proinflammatory State

Context: Type 1 diabetes (T1DM) is associated with increased cardiovascular mortality. It is a pro-inflammatory state as evidenced by increased circulating biomarkers and monocyte activity. The toll-like receptors (TLRs) are pattern recognition receptors, expressed abundantly on monocytes. TLR2 and...

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Detalhes bibliográficos
Main Authors: Devaraj, Sridevi, Dasu, Mohan R., Rockwood, Jason, Winter, William, Griffen, Steven C., Jialal, Ishwarlal
Formato: Artigo
Idioma:Inglês
Publicado em: The Endocrine Society 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2243229/
https://ncbi.nlm.nih.gov/pubmed/18029454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jc.2007-2185
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