Salp15 Binding to DC-SIGN Inhibits Cytokine Expression by Impairing both Nucleosome Remodeling and mRNA Stabilization

Ixodes ticks are major vectors for human pathogens, such as Borrelia burgdorferi, the causative agent of Lyme disease. Tick saliva contains immunosuppressive molecules that facilitate tick feeding and B. burgdorferi infection. We here demonstrate, to our knowledge for the first time, that the Ixodes...

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Hlavní autoři: Hovius, Joppe W. R, de Jong, Marein A. W. P, den Dunnen, Jeroen, Litjens, Manja, Fikrig, Erol, van der Poll, Tom, Gringhuis, Sonja I, Geijtenbeek, Teunis B. H
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2008
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2242833/
https://ncbi.nlm.nih.gov/pubmed/18282094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.0040031
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