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Expression Profiles Reveal Parallel Evolution of Epistatic Interactions Involving the CRP Regulon in Escherichia coli

The extent and nature of epistatic interactions between mutations are issues of fundamental importance in evolutionary biology. However, they are difficult to study and their influence on adaptation remains poorly understood. Here, we use a systems-level approach to examine epistatic interactions th...

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Detalles Bibliográficos
Main Authors: Cooper, Tim F, Remold, Susanna K, Lenski, Richard E, Schneider, Dominique
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2008
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2242816/
https://ncbi.nlm.nih.gov/pubmed/18282111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.0040035
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