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Implication of BRCA2 -26G>A 5' untranslated region polymorphism in susceptibility to sporadic breast cancer and its modulation by p53 codon 72 Arg>Pro polymorphism

INTRODUCTION: The absence of mutation or promoter hypermethylation in the BRCA2 gene in the majority of breast cancer cases has indicated alternative ways of its involvement, deregulated expression being one possibility. We show how a polymorphism in the 5' untranslated region (UTR) of BRCA2 ca...

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Detalhes bibliográficos
Main Authors: Gochhait, Sailesh, Bukhari, Syed Irfan Ahmad, Bairwa, Narendra, Vadhera, Shivani, Darvishi, Katayoon, Raish, Mohammad, Gupta, Pawan, Husain, Syed Akhtar, Bamezai, Rameshwar NK
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2242669/
https://ncbi.nlm.nih.gov/pubmed/17945002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr1780
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