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Comparative analysis and “expression space” coverage of the production of prokaryotic membrane proteins for structural genomics

Membrane proteins comprise up to one-third of prokaryotic and eukaryotic genomes, but only a very small number of membrane protein structures are known. Membrane proteins are challenging targets for structural biology, primarily due to the difficulty in producing and purifying milligram quantities o...

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Bibliographic Details
Main Authors: Surade, Sachin, Klein, Markus, Stolt-Bergner, Peggy C., Muenke, Cornelia, Roy, Ankita, Michel, Hartmut
Format: Artigo
Language:Inglês
Published: Cold Spring Harbor Laboratory Press 2006
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2242615/
https://ncbi.nlm.nih.gov/pubmed/16943447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.062312706
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