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Crystal structure of the yeast His6 enzyme suggests a reaction mechanism

The Saccharomyces cerevisiae His6 gene codes for the enzyme phosphoribosyl-5-amino-1-phosphoribosyl-4-imidazolecarboxamide isomerase, catalyzing the fourth step in histidine biosynthesis. To get an insight into the structure and function of this enzyme, we determined its X-ray structure at a resolut...

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Bibliografiske detaljer
Main Authors: Quevillon-Cheruel, Sophie, Leulliot, Nicolas, Graille, Marc, Blondeau, Karine, Janin, Joel, Tilbeurgh, Herman Van
Format: Artigo
Sprog:Inglês
Udgivet: Cold Spring Harbor Laboratory Press 2006
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2242542/
https://ncbi.nlm.nih.gov/pubmed/16731983
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.062144406
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