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Determination of network of residues that regulate allostery in protein families using sequence analysis
Allosteric interactions between residues that are spatially apart and well separated in sequence are important in the function of multimeric proteins as well as single-domain proteins. This observation suggests that, among the residues that are involved in long-range communications, mutation at one...
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Main Authors: | , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Cold Spring Harbor Laboratory Press
2006
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2242462/ https://ncbi.nlm.nih.gov/pubmed/16434743 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.051767306 |
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