Competition between intercellular adhesion molecule-1 and a small-molecule antagonist for a common binding site on the αl subunit of lymphocyte function-associated antigen-1

The lymphocyte function-associated antigen-1 (LFA-1) binding of a unique class of small-molecule antagonists as represented by compound 3 was analyzed in comparison to that of soluble intercellular adhesion molecule-1 (sICAM-1) and A-286982, which respectively define direct and allosteric competitiv...

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Detalhes bibliográficos
Main Authors: Keating, Susan M., Clark, Kevin R., Stefanich, Lisa D., Arellano, Fred, Edwards, Caroline P., Bodary, Sarah C., Spencer, Steven A., Gadek, Thomas R., Marsters, James C., Beresini, Maureen H.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2006
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2242450/
https://ncbi.nlm.nih.gov/pubmed/16384997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.051583406
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