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NMR characterizations of an amyloidogenic conformational ensemble of the PI3K SH3 domain
Amyloid formation is associated with structural changes of native polypeptides to monomeric intermediate states and their self-assembly into insoluble aggregates. Characterizations of the amyloidogenic intermediate state are, therefore, of great importance in understanding the early stage of amyloid...
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| Autors principals: | , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Blackwell Publishing
2006
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2242406/ https://ncbi.nlm.nih.gov/pubmed/17001038 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.062154306 |
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