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NMR characterizations of an amyloidogenic conformational ensemble of the PI3K SH3 domain

Amyloid formation is associated with structural changes of native polypeptides to monomeric intermediate states and their self-assembly into insoluble aggregates. Characterizations of the amyloidogenic intermediate state are, therefore, of great importance in understanding the early stage of amyloid...

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Autori principali: Ahn, Hee-Chul, Le, Yen T.H., Nagchowdhuri, Partha S., DeRose, Eugene F., Putnam-Evans, Cindy, London, Robert E., Markley, John L., Lim, Kwang Hun
Natura: Artigo
Lingua:Inglês
Pubblicazione: Blackwell Publishing 2006
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2242406/
https://ncbi.nlm.nih.gov/pubmed/17001038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.062154306
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