Combinatorial Domain Hunting: An effective approach for the identification of soluble protein domains adaptable to high-throughput applications

Exploitation of potential new targets for drug and vaccine development has an absolute requirement for multimilligram quantities of soluble protein. While recombinant expression of full-length proteins is frequently problematic, high-yield soluble expression of functional subconstructs is an effecti...

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Detalhes bibliográficos
Main Authors: Reich, Stefanie, Puckey, Loretto H., Cheetham, Caroline L., Harris, Richard, Ali, Ammar A.E., Bhattacharyya, Uma, Maclagan, Kate, Powell, Keith A., Prodromou, Chrisostomos, Pearl, Laurence H., Driscoll, Paul C., Savva, Renos
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2006
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2242398/
https://ncbi.nlm.nih.gov/pubmed/17008718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.062082606
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