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Localization of binding sites in protein structures by optimization of a composite scoring function

The rise in the number of functionally uncharacterized protein structures is increasing the demand for structure-based methods for functional annotation. Here, we describe a method for predicting the location of a binding site of a given type on a target protein structure. The method begins by const...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Rossi, Andrea, Marti-Renom, Marc A., Sali, Andrej
Format: Artigo
Langue:Inglês
Publié: Blackwell Publishing 2006
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2242385/
https://ncbi.nlm.nih.gov/pubmed/16963645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.062247506
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