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Diversity of preferred nucleotide sequences around the translation initiation codon in eukaryote genomes

Understanding regulatory mechanisms of protein synthesis in eukaryotes is essential for the accurate annotation of genome sequences. Kozak reported that the nucleotide sequence GCCGCC(A/G)CCAUGG (AUG is the initiation codon) was frequently observed in vertebrate genes and that this ‘consensus’ seque...

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Autori principali: Nakagawa, So, Niimura, Yoshihito, Gojobori, Takashi, Tanaka, Hiroshi, Miura, Kin-ichiro
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2241899/
https://ncbi.nlm.nih.gov/pubmed/18086709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkm1102
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