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Cigarette smoke inhibits macrophage sensing of Gram-negative bacteria and lipopolysaccharide: relative roles of nicotine and oxidant stress

BACKGROUND AND PURPOSE: Smoking cigarettes is a major risk factor for the development of cardiovascular and respiratory disease. Moreover, smokers are more prone to infections. This has been associated with a suppression of the immune system by smoke. However, it is not clear how cigarette smoke aff...

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Main Authors: McMaster, S K, Paul-Clark, M J, Walters, M, Fleet, M, Anandarajah, J, Sriskandan, S, Mitchell, J A
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2007
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2241791/
https://ncbi.nlm.nih.gov/pubmed/18059323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0707595
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