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3′ end mRNA processing: molecular mechanisms and implications for health and disease

Recent advances in the understanding of the molecular mechanism of mRNA 3′ end processing have uncovered a previously unanticipated integrated network of transcriptional and RNA-processing mechanisms. A variety of human diseases impressively reflect the importance of the precision of the complex 3′...

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Autori principali: Danckwardt, Sven, Hentze, Matthias W, Kulozik, Andreas E
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2241648/
https://ncbi.nlm.nih.gov/pubmed/18256699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601932
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