Decreased Substance P and NK1 Receptor Immunoreactivity and Function in the Spinal Cord Dorsal Horn of Morphine-Treated Neonatal Rats

Opiate analgesic tolerance is defined as a need for higher doses of opiates to maintain pain relief following prolonged opiate exposure. Though changes in the opioid receptor undoubtedly occur during conditions of opiate tolerance, there is increasing evidence that opiate analgesic tolerance is also...

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Detalhes bibliográficos
Main Authors: Thomson, Lisa M., Terman, Gregory W., Zeng, Jinsong, Lowe, Janet, Chavkin, Charles, Hermes, Sam M., Hegarty, Deborah M., Aicher, Sue A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2241645/
https://ncbi.nlm.nih.gov/pubmed/17950674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jpain.2007.07.008
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