Decreased Substance P and NK1 Receptor Immunoreactivity and Function in the Spinal Cord Dorsal Horn of Morphine-Treated Neonatal Rats

Opiate analgesic tolerance is defined as a need for higher doses of opiates to maintain pain relief following prolonged opiate exposure. Though changes in the opioid receptor undoubtedly occur during conditions of opiate tolerance, there is increasing evidence that opiate analgesic tolerance is also...

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Bibliografiske detaljer
Main Authors: Thomson, Lisa M., Terman, Gregory W., Zeng, Jinsong, Lowe, Janet, Chavkin, Charles, Hermes, Sam M., Hegarty, Deborah M., Aicher, Sue A.
Format: Artigo
Sprog:Inglês
Udgivet: 2007
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2241645/
https://ncbi.nlm.nih.gov/pubmed/17950674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jpain.2007.07.008
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