MED1, a novel human methyl-CpG-binding endonuclease, interacts with DNA mismatch repair protein MLH1

The DNA mismatch repair (MMR) is a specialized system, highly conserved throughout evolution, involved in the maintenance of genomic integrity. To identify novel human genes that may function in MMR, we employed the yeast interaction trap. Using the MMR protein MLH1 as bait, we cloned MED1. The MED1...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Bellacosa, Alfonso, Cicchillitti, Lucia, Schepis, Filippo, Riccio, Antonio, Yeung, Anthony T., Matsumoto, Yoshihiro, Golemis, Erica A., Genuardi, Maurizio, Neri, Giovanni
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1999
Assuntos:	Biological Sciences
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC22404/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10097147/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.7.3969
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