Reactivation of Kaposi's sarcoma-associated herpesvirus from latency requires MEK/ERK, JNK and p38 multiple mitogen-activated protein kinase pathways

Lytic replication of Kaposi's sarcoma-associated herpesvirus (KSHV) promotes the progression of Kaposi's sarcoma (KS), a dominant malignancy in patients with AIDS. While 12-O-tetradecanoyl-phorbol-13-acetate (TPA)-induced KSHV reactivation from latency is mediated by the protein kinase C δ...

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Bibliographic Details
Main Authors: Xie, Jianping, Ajibade, Adetola Olalekan, Ye, Fengchun, Kuhne, Kurt, Gao, Shou-Jiang
Format: Artigo
Language:Inglês
Published: 2007
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2239004/
https://ncbi.nlm.nih.gov/pubmed/17964626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2007.09.040
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