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FOXP3 Promoter Demethylation Reveals the Committed Treg Population in Humans
BACKGROUND: Naturally occurring thymus derived regulatory T cells (Tregs) are central in the maintenance of self-tolerance. The transcription factor FOXP3 is crucial for the suppressive activity of Tregs and is considered the most specific marker for this population. However, human non regulatory T...
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| Hauptverfasser: | , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Public Library of Science
2008
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2238816/ https://ncbi.nlm.nih.gov/pubmed/18286169 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0001612 |
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