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Identification of a PTEN-regulated STAT3 brain tumor suppressor pathway

Activation of the transcription factor STAT3 is thought to potently promote oncogenesis in a variety of tissues, leading to intense efforts to develop STAT3 inhibitors for many tumors, including the highly malignant brain tumor glioblastoma. However, the function of STAT3 in glioblastoma pathogenesi...

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Detalhes bibliográficos
Main Authors: de la Iglesia, Núria, Konopka, Genevieve, Puram, Sidharth V., Chan, Jennifer A., Bachoo, Robert M., You, Mingjian J., Levy, David E., DePinho, Ronald A., Bonni, Azad
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2238667/
https://ncbi.nlm.nih.gov/pubmed/18258752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1606508
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