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Identification of a PTEN-regulated STAT3 brain tumor suppressor pathway
Activation of the transcription factor STAT3 is thought to potently promote oncogenesis in a variety of tissues, leading to intense efforts to develop STAT3 inhibitors for many tumors, including the highly malignant brain tumor glioblastoma. However, the function of STAT3 in glioblastoma pathogenesi...
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Main Authors: | , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Cold Spring Harbor Laboratory Press
2008
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2238667/ https://ncbi.nlm.nih.gov/pubmed/18258752 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1606508 |
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