A Point Mutation in the Two-Component Regulator PhoP-PhoR Accounts for the Absence of Polyketide-Derived Acyltrehaloses but Not That of Phthiocerol Dimycocerosates in Mycobacterium tuberculosis H37Ra

Similarities between Mycobacterium tuberculosis phoP-phoR mutants and the attenuated laboratory strain M. tuberculosis H37Ra in terms of morphological and cytochemical properties, lipid content, gene expression and virulence attenuation prompted us to analyze the functionality of this two-component...

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Hlavní autoři: Chesne-Seck, Marie-Laure, Barilone, Nathalie, Boudou, Frédéric, Asensio, Jesús Gonzalo, Kolattukudy, Pappachan E., Martín, Carlos, Cole, Stewart T., Gicquel, Brigitte, Gopaul, Deshmukh N., Jackson, Mary
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 2008
Témata:
Genetics and Molecular Biology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2238218/
https://ncbi.nlm.nih.gov/pubmed/18065542
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.01465-07
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