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Effect of Hydroxyurea on Procyclic Trypanosoma brucei: an Unconventional Mechanism for Achieving Synchronous Growth
Procyclic Trypanosoma brucei cells were synchronized with 0.2 mM hydroxyurea. The cells did not arrest at the G(1)/S boundary but proceeded through one round of replication and arrested near the end of S phase. The mitochondrial genome (kinetoplast DNA network) replicated, forming two progeny networ...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Microbiology (ASM)
2008
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2238168/ https://ncbi.nlm.nih.gov/pubmed/18083826 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/EC.00369-07 |
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