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Disruption of the PfPK7 Gene Impairs Schizogony and Sporogony in the Human Malaria Parasite Plasmodium falciparum

PfPK7 is an orphan protein kinase of Plasmodium falciparum with maximal homology to MEK3/6 and to fungal protein kinase A proteins in its C-terminal and N-terminal regions, respectively. We showed previously that recombinant PfPK7 is active on various substrates but is unable to phosphorylate the Pl...

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Bibliographic Details
Main Authors: Dorin-Semblat, Dominique, Sicard, Audrey, Doerig, Caroline, Ranford-Cartwright, Lisa, Doerig, Christian
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 2008
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2238148/
https://ncbi.nlm.nih.gov/pubmed/18083830
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/EC.00245-07
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