Development of Multiplex Assay for Rapid Characterization of Mycobacterium tuberculosis

We have developed a multiplex assay, based on multiplex ligation-dependent probe amplification (MLPA), that allows simultaneous detection of multiple drug resistance mutations and genotype-specific mutations at any location in the Mycobacterium tuberculosis genome. The assay was validated on a refer...

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Bibliographic Details
Main Authors: Bergval, I. L., Vijzelaar, R. N. C. P., Dalla Costa, E. R., Schuitema, A. R. J., Oskam, L., Kritski, A. L., Klatser, P. R., Anthony, R. M.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 2008
Subjects:
Mycobacteriology and Aerobic Actinomycetes
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2238130/
https://ncbi.nlm.nih.gov/pubmed/18077627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JCM.01821-07
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