Scar, a WASp-related protein, activates nucleation of actin filaments by the Arp2/3 complex

The Arp2/3 complex, a stable assembly of two actin-related proteins (Arp2 and Arp3) with five other subunits, caps the pointed end of actin filaments and nucleates actin polymerization with low efficiency. WASp and Scar are two similar proteins that bind the p21 subunit of the Arp2/3 complex, but th...

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Bibliografiska uppgifter
Huvudupphovsmän: Machesky, Laura M., Mullins, R. Dyche, Higgs, Henry N., Kaiser, Donald A., Blanchoin, Laurent, May, Robin C., Hall, Margaret E., Pollard, Thomas D.
Materialtyp: Artigo
Språk:Inglês
Publicerad: The National Academy of Sciences 1999
Ämnen:
Biological Sciences
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC22364/
https://ncbi.nlm.nih.gov/pubmed/10097107
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