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ON THE MECHANISM OF PEPSIN ACTION

The problem of the mechanism of pepsin action is considered in relation to recent data on the kinetics and specificity of the enzyme, as well as the finding, reported here, that pepsin exhibits a deuterium isotope effect in the cleavage of a peptide bond. The kinetic parameters for the hydrolysis of...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Hollands, T. Ralph, Fruton, Joseph S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 1969
Schlagworte:
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC223622/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4894688/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.62.4.1116
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