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Import of DNA into mammalian nuclei by proteins originating from a plant pathogenic bacterium

Import of DNA into mammalian nuclei is generally inefficient. Therefore, one of the current challenges in human gene therapy is the development of efficient DNA delivery systems. Here we tested whether bacterial proteins could be used to target DNA to mammalian cells. Agrobacterium tumefaciens, a pl...

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Detalhes bibliográficos
Main Authors: Ziemienowicz, Alicja, Görlich, Dirk, Lanka, Erich, Hohn, Barbara, Rossi, Luca
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC22362/
https://ncbi.nlm.nih.gov/pubmed/10097105
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