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Incomplete depletion and rapid regeneration of Foxp3+ regulatory T cells following anti-CD25 treatment in malaria-infected mice

Investigation of the role of regulatory T cells (Treg) in model systems is facilitated by their depletion using anti-CD25 antibodies, but there has been considerable debate about the effectiveness of this strategy. Here, we have compared the depletion and repopulation of CD4(+)CD25(+)Foxp3(+) Treg i...

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Autors principals: Couper, Kevin N., Blount, Daniel G., de Souza, J. Brian, Suffia, Isabelle, Belkaid, Yasmine, Riley, Eleanor M.
Format: Artigo
Idioma:Inglês
Publicat: 2007
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2235934/
https://ncbi.nlm.nih.gov/pubmed/17371969
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