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HTLV-1 HBZ cooperates with JunD to enhance transcription of the human telomerase reverse transcriptase gene (hTERT)

BACKGROUND: Activation of telomerase is a critical and late event in tumor progression. Thus, in patients with adult-T cell leukaemia (ATL), an HTLV-1 (Human T cell Leukaemia virus type 1)-associated disease, leukemic cells display a high telomerase activity, mainly through transcriptional up-regula...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Kuhlmann, Anne-Sophie, Villaudy, Julien, Gazzolo, Louis, Castellazzi, Marc, Mesnard, Jean-Michel, Duc Dodon, Madeleine
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2007
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2235888/
https://ncbi.nlm.nih.gov/pubmed/18078517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4690-4-92
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